What is Multiple
Sclerosis?
An unpredictable
disease of the
central nervous
system, multiple
sclerosis (MS) can
range from
relatively benign to
somewhat disabling
to devastating, as
communication
between the brain
and other parts of
the body is
disrupted. Many
investigators
believe MS to be an
autoimmune disease
-- one in which the
body, through its
immune system,
launches a defensive
attack against its
own tissues. In the
case of MS, it is
the nerve-insulating
myelin that comes
under assault. Such
assaults may be
linked to an unknown
environmental
trigger, perhaps a
virus.
The central
nervous system
consists of the
brain, spinal cord,
and the optic
nerves. Surrounding
and protecting the
nerve fibers of the
central nervous
system is a fatty
tissue called
myelin, which helps
nerve fibers conduct
electrical impulses.
When myelin or the
nerve fiber is
destroyed or
damaged, the ability
of the nerves to
conduct electrical
impulses to and from
the brain is
disrupted, and this
produces the various
symptoms of MS. In
the condition of MS,
myelin is lost in
multiple areas,
leaving scar tissue
called sclerosis.
Most people
experience their
first symptoms of MS
between the ages of
20 and 40.
Symptoms of Multiple
Sclerosis (MS) may
be unpredictable and
may vary. One person
may experience
abnormal fatigue,
while another might
have severe vision
problems. A person
with MS could have
loss of balance and
muscle coordination
making walking
difficult; another
person with MS could
have slurred speech,
tremors, stiffness,
and bladder
problems. Even
severe symptoms may
disappear completely
and the person will
regain lost
functions.
Common symptoms may
include bladder and
bowel dysfunction,
cognitive problems,
dizziness, vertigo,
emotional problems,
fatigue,
gait/walking
problems, hearing
loss, itching,
headache, numbness,
pain, seizures,
sexual dysfunction,
speech and
swallowing
disorders, tremors
and vision problems.
What is the
prognosis?
The
cause of Multiple
Sclerosis is
relatively unknown.
Researchers believe
that the damage to
myelin results from
an abnormal response
by the body’s immune
system. Normally,
the immune system
defends the body
against foreign
invaders such as
viruses or bacteria.
In autoimmune
diseases, the body
attacks its own
tissue. It is
believed that MS is
an autoimmune
disease, and in this
case, myelin is
attacked. Scientists
do not yet know what
triggers the immune
system to do this.
Most agree that
several factors are
involved, which
include
environmental
triggers, such as
trauma, toxins,
virus', heavy metals
and in some cases
genetics.
There is no
definitive link to
one virus or another
which could be
responsible for the
demyelination
(destruction of the
myelin sheath
surrounding and
insulating the nerve
fibers of the
central nervous
system) as seen in
MS. At one time or
another, canine
distemper virus,
measles virus,
herpes virus
(HHV-6), rubella (or
German measles)
virus, HTLV-1 virus,
Epstein Barr virus,
and others have been
reported to be
associated with MS.
Yet there is no
proof that any of
them causes MS.
The
role of trauma in
causing MS or in
triggering
subsequent MS
exacerbations (also
known as attacks,
relapses or flares)
has been the subject
of controversy for
many years. There is
no direct evidenced
in research findings
that directly
relates trauma to
the onset or
flare-up of multiple
sclerosis. Trauma is
multi-faceted and
its impact in the
development and
reoccurrence of MS
is still being
explored. It is
accepted belief to
say that stress and
poor nutrition can
often precede an
occurrence of MS
A physician may
diagnose MS in some
patients soon after
the onset of the
illness. In others,
however, doctors may
not be able to
readily identify the
cause of the
symptoms, leading to
years of uncertainty
and multiple
diagnoses punctuated
by baffling symptoms
that mysteriously
wax and wane. The
vast majority of
patients are mildly
affected, but in the
worst cases, MS can
render a person
unable to write,
speak, or walk. MS
is a disease with a
natural tendency to
remit spontaneously,
for which there is
no universally
effective treatment.
Is there any
treatment?
There is as yet no
cure for MS. Many
patients do well
with no therapy at
all, especially
since many
medications have
serious side effects
and some carry
significant risks. |